Frederic Mohs: Chemosurgery Book
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By F. E. MOHS, B.Sc., M.D. Pp. xvii + 305, with 225 illustrations. Oxford: Blackwell Scientific Publications Ltd. I956.


This book by Frederic Mohs features his results of a 12,000 person study using the herb bloodroot and zinc chloride to destroy cancer cells.

According to Wikipedia, Mohs surgery, also known as chemosurgery, developed in 1938 by a general surgeon, Dr. Frederic E. Mohs, is microscopically controlled surgery used to treat common types of skin cancer. Mohs surgery is one of the many methods of obtaining complete margin control during removal of a skin cancer. Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.

The cure rate with Mohs surgery cited by most studies is between 97% and 99.8% for primary basal cell carcinoma, the most common type of skin cancer. Recurrent basal cell cancer has a lower cure rate with Mohs surgery, more in the range of 94%. It has been used in the removal of melanoma-in-situ (cure rate 77% to 98% depending on surgeon), and certain types of melanoma (cure rate 52%). Another study of melanoma-in-situ revealed Mohs cure rate of 95% for frozen section Mohs, and 98 to 99% for fixed tissue Mohs method.

Other indications for Mohs surgery include dermatofibrosarcoma protuberans, keratoacanthoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, leiomyosarcoma, and angiosarcoma. Because the Mohs procedure is micrographically controlled, it provides precise removal of the cancerous tissue, while healthy tissue is spared. Mohs surgery is also more cost effective to other surgical methods when considering the cost of surgical removal, and separate histopathological analysis. However, Mohs surgery should be reserved for the treatment of skin cancers in anatomic areas where tissue preservation is of utmost importance (Face, hands, feet, genitals).



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